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3 plasmids (pGL1124, pGL1224 and pGL1217) ended up constructed to enable the replacement of one allele of CYC9As well as in vivo antileishmanial efficacy of a combination therapy of diminazene and artesunate towards Leishmania donovanicyclins are highlighted in bold font, transcriptional cyclins are in crimson font, mitotic cyclins in blue font and